Our experience manufacturing bifurcated needles for smallpox makes us a logical choice to make needles for the skin prick allergy test. Instead of puncturing the skin one time, the person administering the vaccine … By the 1940s, Wyeth was the leading U.S. manufacturer of the vaccine and the only manufacturer by the 1960s. Our engineers designed the needle, and our team of machinists and metalworkers perfected to how to manufacture it in bulk.

(Duration 5:58) Chapter 2, Part C: Interpreting Smallpox Vaccination Results external icon. Then came the terrorist attacks of September 11, 2001, and the global turmoil that followed. He observed that milkmaids who previously had caught cowpox did not catch smallpox … It was one of the deadliest diseases known to humans, and to date (2016) the only human disease to have been eradicated by vaccination. Bifurcated needle vaccination required one-fourth the amount of vaccine needed with previous methods and was simpler to perform. The project still stands as one of our most significant achievements — and a testament to the knowledge and expertise that PMP brings to every medical device manufacturing challenge. The smallpox vaccine is given using a special bifurcated (two-prong) needle. Before the 1960s, smallpox vaccination campaigns relied on unreliable jet injectors that slowed delivery of the vaccine. To hit the target, PMP would have to make 25 million needles a month, which breaks down to almost six million a week and more than 800,000 per day! Alcohol will inactivate the vaccinia virus. Dryvax is a freeze-dried calf lymph smallpox vaccine. Before the 1960s, smallpox vaccination campaigns relied on unreliable jet injectors that slowed delivery of the vaccine. Shown here is a scanning electron microscope photograph of a bifurcated needle. The needle is designed to hold a tiny drop of vaccine of sufficient size and strength to ensure a successful vaccination … Actually, it only took our team 11 months, and we even improved on the packaging. Learn how to administer the ACAM2000 smallpox vaccine using a bifurcated needle and the multiple-puncture technique. Our needles are inexpensive, minimally invasive, and produce results in 15 to 20 minutes. Faced with the possibility that terrorists might use smallpox as a bio-weapon, the U.S. government turned to Precision Medical Products, Inc., with a new challenge: produce enough bifurcated needles — 400 million — in one year to inoculate the entire nation. You can learn more about this time in PMP’s history by watching this short video. The history of smallpox holds a unique place in medicine. Interpret the response to smallpox vaccination with ACAM2000. After world health authorities declared smallpox had been eradicated from nature in 1980, Wyeth stopped making the vaccine. The needle was a cost-effective alternative to a clunky, unreliable jet injector that had been slowing down vaccination campaigns. Benjamin Rubin, MD, of Wyeth Laboratories patented the bifurcated needle for delivery of smallpox vaccine. It is the world's oldest smallpox vaccine, created in the late 19th century by American Home Products, a predecessor of Wyeth. Precision Medical Products, Inc., changed that with the introduction of the bifurcated needle, which holds a dose of reconstituted smallpox vaccine in its prongs and punctures a person’s skin easily to the ideal depth for delivery.


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