ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. URL: https://www.sciencedirect.com/science/article/pii/B978012800883600032X, URL: https://www.sciencedirect.com/science/article/pii/B9780123815101001083, URL: https://www.sciencedirect.com/science/article/pii/B9780444563781000587, URL: https://www.sciencedirect.com/science/article/pii/B9780123815101000831, URL: https://www.sciencedirect.com/science/article/pii/B9780128098417000095, URL: https://www.sciencedirect.com/science/article/pii/B9780121348366500135, URL: https://www.sciencedirect.com/science/article/pii/B9780123849373001087, URL: https://www.sciencedirect.com/science/article/pii/B9780126569704500488, URL: https://www.sciencedirect.com/science/article/pii/B9781416036616000018, Quantitative Human Physiology (Second Edition), Considerable intrinsic diversity is found among, Smooth Muscle Myocyte Ultrastructure and Contractility, Fundamentals of Toxicologic Pathology (Third Edition), Nutritional Biochemistry (Second Edition), Green Tea (−)-Epigallocatechin-3-Gallate and its Effects on Pancreatic Stellate Cells, Asaumi et al., 2007; Watanabe et al., 2004. Histology Guide © Faculty of Biological Sciences, University of Leeds | Credits. This diagram shows a few of the cells that can be seen in the stained section below. ), R. Kent Hermsmeyer, in Cell Physiology Source Book, 1995. Smooth muscles can develop and maintain this force at surprisingly low adenosine triphosphate (ATP) consumption (JATP = 1.2 µmol/g/min). Serum SMA are detectable in a large number of the patients with AIH, usually at titers higher than 1:80 and often associated with ANA [9]. The myoepithelial cells are very thin, and have dense flattened nuclei. With the multiplicity of receptors and response mechanisms found in the deceptively small smooth muscle cell, the complexity of signaling mechanisms possible with the simple smooth muscle spike should be regarded as a compact masterpiece of multiple responsiveness. The cells stick together and are connected by specialised Figure 108.7. Smooth muscle varies its force through recruitment of cross-bridges by phosphorylating the myosin light chains, which is controlled by Ca2+. These cells have fibers of actin and myosin which run through the cell and are supported by a framework of other proteins. Answer: Smooth muscle cells usually have one nucleus per cell and the nucleus resides in the center of the cell. This diagram shows a few of the cells that can be seen in the stained section below. SMA, usually with a V pattern and at low titer, are also a common finding during viral diseases such as infectious mononucleosis and chronic hepatitis C (8–10%), as well as in several rheumatologic and neoplastic diseases.

SMA of the IgA class with antiactin specificity are detected in patients with celiac disease at the time of diagnosis, especially when the mucosal damage is particularly severe, whereas after gluten-free diet they tend to disappear [5].

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