Extramedullary hematopoiesis refers to hematpoiesis in locations other than the bone marrow medullary space. Conclusion: Patients presenting with the lower extremity symptoms/signs, ranging from low back pain to neurogenic claudication and even paraplegia, may have EH secondary to TM. Myelolipoma is a benign tumor of adrenal gland, usually an incidental autopsy finding. Learn more about Institutional Access, Frans H. Krouwels, M.D.Paul Bresser, M.D.Albert E.G.K. EMH is normally seen during embryonic development and fetal life.

Activate your online access. Munn RK, Kramer CA, Arnold SM. Extramedullary myeloma is an unusual presentation of MM, and little is known about its incidence and natural history. These masses were characterized by a proliferation of pleomorphic, large cells, and fibrosis that infiltrated, surrounded, and replaced the normal tissue. Correspondence Address:Bharath RajuDepartment of Neurosurgery, Rutgers Robert Wood Johnson University Hospital, New Brunswick, New Jersey, United States.

Interestingly, subdural hemorrhage/hematoma can be a secondary process of EMH in patients with hematopoietic disorders [8, 9]. However, the clusters of nucleated red blood cells can present a diagnostic pitfall for surgical pathologists as the common differential diagnoses of groups of small round cells with hyperchromatic nuclei and scant cytoplasm in the subdural space include metastatic malignant tumors, such as small cell carcinoma, melanoma, and/or lymphoma. The first report of EMH in a subdural hematoma was published in 1966 [2] in a 4-month old infant who was very anemic and presented with an enlarged head with a persistent subdural hematoma. Review articles are excluded from this waiver policy. However, negative immunostains for epithelial, neuroendocrine, mesenchymal, and lymphoid markers help to rule out these possibilities.

Extramedullary hematopoiesis refers to hematpoiesis in locations other than the bone marrow medullary space. This phenomenon has been observed in lung tissue following bone fracture or cardiac surgery and in the presacral area following a sacrum fracture [7]. These hematomas can resolve spontaneously if small. Lippincott Williams & Wilkins. The clinical significance of the EMH in subdural hematoma is thought to be of no importance as concluded in one previous report [3]. In . This article has no abstract; the first 100 words appear below. Case report,”, W. Muller, E. Zimmermann, and R. Firsching, “Erythropoiesis in chronic subdural haematomas,”, R. Firsching, W. Müller, F. Thun, and F. Boop, “Clinical correlates of erythropoiesis in chronic subdural hematoma,”, E. Kuhn, T. Dorji, J. Rodriguez, and J. Rosai, “Extramedullary erythropoiesis in chronic subdural hematoma simulating metastatic small round cell tumor,”, C. A. Koch, C. Y. Li, R. A. Mesa, and A. Tefferi, “Nonhepatosplenic extramedullary hematopoiesis: associated diseases, pathology, clinical course, and treatment,”, N. Forster and O. Schöb, “Incidental discovery of presacral tumour in a healthy patient: extramedullary haematopoiesis caused by a sacral fracture?”, J.

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