The main use of BCG is for vaccination against tuberculosis.BCG vaccine can be administered after birth intradermally. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.

We conducted a population-based case-control study of protection by BCG given to children aged 12-13 years against tuberculosis occurring 10-29 years later.

Commonly reported side effects of bcg include: urinary tract infection, detrusor hyperreflexia of bladder, fever, hematuria, urinary frequency, urinary urgency, vomiting, chills, and malaise. Search for other works by this author on: Institute for Global Health, University College London, Correspondence: C. Jackson, PhD, Institute for Global Health, University College London, London WC1E 6BT, UK (, National Infection Service, Public Health England, National Institute for Health Research Health Protection Research Unit in Respiratory Infections, Imperial College, University College London Respiratory, Division of Medicine, University College London, Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine. They can range from very mild to serious. Cerner Multum, Inc. "UK Summary of Product Characteristics."

NIH

School-aged BCG vaccination offered moderate protection against tuberculosis for at least 20 years, which is longer than previously thought. 2005 Dec;77(4):215-8. J Trop Med. 4 This should be particularly useful in communities where BCG vaccination is universal. HHS Organon, West Orange, NJ. You may report them to the FDA.

[Chemo-immunoprevention in superficial bladder cancer]. Last updated on Jul 21, 2020. BCG Vaccine (BCG)." About 2 to 6 weeks after the injection, a small spot may appear at the site of the injection. Evidence of protection from childhood Bacillus Calmette-Guerin (BCG) against tuberculosis (TB) in adulthood, when most transmission occurs, is important for TB control and resource allocation. Clipboard, Search History, and several other advanced features are temporarily unavailable. If you do, they may appear soon after treatment or up to years after treatment ends. Saralahti AK, Uusi-Mäkelä MIE, Niskanen MT, Rämet M. Dis Model Mech.

2012 Dec;64(4):255-60. Hazard ratios and 95% confidence intervals (CIs) were estimated using case-cohort Cox regression, adjusting for potential confounding factors, including socio-economic status, smoking, drug use, prison and homelessness. During the same period, 1456 vaccines were administered, with a prevalence of 0.046% adverse reactions; of the patients with these adverse reactions, 45 had local reactions, 18 had lymphadenopathy, 3 had combined local reactio… See below for a comprehensive list of adverse effects. Lanckriet C, Lévy-Bruhl D, Bingono E, Siopathis RM, Guérin N. Int J Epidemiol. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

In participants vaccinated at age >2 years, the protective association was greatest in those vaccinated ≤10 years ago (OR, 0.31; 95% CI, .15–.63), versus those vaccinated 11–20 and >20 years ago (OR, 0.73; 95% CI, .48–1.10, and OR, 0.67; 95% CI, .46–.98, respectively). Medically reviewed by Drugs.com. In total 10,000 contacts will be included in both intervention arms over a 2-year period. 2020 Jan 30;10:3154. doi: 10.3389/fmicb.2019.03154. Conclusions: eCollection 2019. We obtained 677 cases and 1170 controls after a 65% response rate in both groups.

Martinez-Piñeiro JA.

We were unable to ascertain the strain, the dose and the method of administration of BCG vaccine in these women, although the most … Nguipdop-Djomo P, Heldal E, Rodrigues LC, Abubakar I, Mangtani P. Lancet Infect Dis.

The primary outcome is the occurrence of clinical leprosy within two years.

Sci Rep. 2019 Mar 19;9(1):4842. doi: 10.1038/s41598-019-41008-4. Vaccine effectiveness (VE) of BCG, ascertained based on presence of a scar or vaccination history, against latent tuberculosis infection (LTBI), measured via IGRA, was assessed using multivariable logistic regression. Note: This document contains side effect information about bcg. Drug class: miscellaneous antineoplastics, Burning during first urination after treatment. Methods: To purchase short term access, please sign in to your Oxford Academic account above.

Sometimes, a scar can make the skin feel very tight. 2019 Jul 3;2019:1273235. doi: 10.1155/2019/1273235.

J Clin Invest. During this period of time, Check with your doctor immediately if you notice the following side effects: Applies to bcg: intravesical powder for reconstitution, percutaneous powder for injection, Very common (10% or more): Dysuria (60%), increased urgency/frequency (40%), drug induced cystitis (30%), bacterial cystitis (27%), hematuria (27%), pollakiuria, Common (1% to 10%): Urinary tract infection, urinary incontinence, micturition urgency, urine analysis abnormal, bladder cramps, hemorrhage cystitis, urinary retention, Uncommon (0.1% to 1%): Bladder constriction, pyuria, ureteric obstruction, Rare (0.01 to less than 0.1%): Epididymitis, Very rare (less than 0.01%): Orchitis, balanoposthitis, prostatitis, vulvovaginal discomfort[Ref], Very common (10% or more): Malaise/fatigue/lethargy (19%), fever without infection (13%), influenza-like illness, pyrexia, rigors, Very rare (less than 0.01%): Reiter's syndrome, chest pain, peripheral edema, prostate specific antigen increased, weight decreased, BCG osteomyelitis[Ref], Very rare (less than 0.01%): Dysesthesia, hyperesthesia, paresthesia, somnolence, headache[Ref], Uncommon (0.1% to 1%): Pancytopenia, thrombocytopenia, Very rare (less than 0.01%): Lymphadenopathy, Frequency not reported: Axillary or cervical lymphadenopathy, regional suppurative lymphadenitis[Ref], Common (1% to 10%): Abdominal pain, nausea, vomiting, diarrhea, Very rare (less than 0.01%): Dyspepsia, flatulence[Ref], Uncommon (0.1% to 1%): Tuberculosis infections, Very rare (less than 0.01%): Disseminated BCG infection[Ref], Uncommon (0.1% to 1%): Rashes, eruptions and exanthema not otherwise classified, Very rare (less than 0.01%): Lupus vulgaris, alopecia, hyperhidrosis, granuloma[Ref], Very rare (less than 0.01%): Pharyngitis, bronchitis, dyspnea, rhinitis[Ref], Very rare (less than 0.01%): Renal failure acute[Ref], Common (1% to 10%): Arthralgia, arthritis, myalgia, Very rare (less than 0.01%): Back pain[Ref], Common (1% to 10%): Allergic symptoms[Ref], Uncommon (0.1% to 1%): Hepatitis, hepatic enzyme increased[Ref], Very rare (less than 0.01%): Hypotension[Ref], Very rare (less than 0.01%): Confusional state[Ref], Very rare (less than 0.01%): Anorexia[Ref], Very rare (less than 0.01%): Conjunctivitis[Ref], Frequency not reported: Injection site reactions: Induration, pustule formation, ulceration, caseous lesions, purulent draining, tenderness, itching, papules[Ref], 1.

The Danish strain of BCG vaccine, compared to BCG Russia, has been shown to elicit stronger responses in infants one year later and to cause more scarring , , , , , and the intradermal route of administration is associated with the formation of distinctive scars , . Not all cancer survivors will experience late effects.

See below for a comprehensive list of adverse effects. Serious and fatal disseminated BCG infections have occurred with intravesical administration.

Conservative treatment of high grade superficial bladder tumours. Annual reproductive cycle of males of the bat Molossusmolossus: Seasonal bimodal polyestry, testicular regression, and some aspects of the hormonal control.

2019 Sep 3;129(9):3482-3491. doi: 10.1172/JCI128877.

Applies to bcg: intravesical powder for suspension, Intravesical route (Powder for Suspension; Powder for Solution).  | 



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