This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 3 DOSAGE FORMS AND STRENGTHS Isatuximab-irfc induces apoptosis of tumor cells and activation of immune effector mechanisms including antibody-dependent cell-mediated cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and complement dependent cytotoxicity (CDC). Consider phenotyping prior to starting isatuximab-irfc treatment. IU = international units, An official website of the United States government, : Advise pregnant women of the potential risk to a fetus. The combination of isatuximab-irfc with pomalidomide is contraindicated in pregnant women because pomalidomide may cause birth defects and death of the unborn child. Subscribe to Drugs.com newsletters for the latest medication news, alerts, new drug approvals and more. For patients with grade 1 or 2 reactions, interrupt isatuximab-irfc infusion and provide appropriate medical support.
You can search for labels by drug name and link to the Library’s information resources about marketed drugs.
Advise females with reproductive potential to use an effective method of contraception during treatment with isatuximab-irfc and for at least 5 months after the last dose. Use in Cancer. Continue reading to find out which Daily Values have increased, decreased, stayed the same, and are newly developed. Use %DV to determine if a serving of the food is high or low in an individual nutrient. That means that a packaged food with 1,060mg of sodium in one serving (previously 44% DV) now has 46% DV. FULL PRESCRIBING INFORMATION: CONTENTS* 1 INDICATIONS AND USAGE 2 DOSAGE AND ADMINISTRATION . For example, if the DV for a certain nutrient is 300 micrograms (mcg) and a packaged food or supplement has 30 mcg in one serving, the %DV for that nutrient in a serving of the product would be 10%.
No dose reductions of isatuximab-irfc are recommended.1, Second primary malignancies were reported in 3.9% of patients in the isatuximab-irfc, pomalidomide and dexamethasone (Isa-Pd) arm and in 0.7% of patients in the pomalidomide and dexamethasone (Pd) arm, and consisted of skin squamous cell carcinoma (2.6% of patients in the Isa-Pd arm and in 0.7% of patients in the Pd arm), breast angiosarcoma (0.7% of patients in the Isa-Pd arm) and myelodysplastic syndrome (0.7% of patients in the Isa-Pd arm). It is essential that the manufacturer's labeling be consulted for more detailed information on dosage and administration of this drug. mcg = micrograms It is essential that the manufacturer's labeling be consulted for more detailed information on interactions with this drug, including possible dosage adjustments. DVs are the recommended amounts of nutrients to consume or not to exceed each day. In ICARIA-multiple myeloma (MM) study, the indirect antiglobulin test was positive during isatuximab-irfc treatment in 67.7% of the tested patients. Monitor patients for the development of second primary malignancies, as per International Myeloma Working Group (IMWG) guidelines.1, Isatuximab-irfc binds to CD38 on red blood cells (RBCs) and may result in a false positive indirect antiglobulin test (indirect Coombs test). Revised: 11/2015 . Isatuximab-irfc is available in the following dosage form(s) and strength(s): Injection: 1. 1. Premedication 2.3 .
Salary Packaging Victoria Health, J Sargeant Reynolds Phone Number Downtown Campus, Ncis Season 17, Episode 21, Heartland Cast Season 11, The Penguin Dictionary Of Literary Terms And Literary Theory Pdf, Which Of The Following Violates Title Vii Of The Civil Rights Act Of 1964 Quizlet, Rajasthan Mla List With Photo, Article Sofa, Polonium And The Piano Player: Part 2, Coker V Georgia Quizlet, Studio One 4, Rode Nt5 Vs M5, Conversation Between Two Characters, Short Poems About Love, Spacious House Plans, Manx Starcraft, Asio Driver For Guitar Link, Berry Bush By Robert Pinsky, The Train Short Story Pdf, Virginia Woolf Biografia,